rplS [2019-07-01 11:08:32]

ribosomal protein

Locus: BSU16040

Isoelectric point: 11.29

Molecular weight: 13.61 kDa

Protein length: 118 aa

Gene length: 357 bp

Function: translation

Product: ribosomal protein L19

Essential: yes

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Ribosomal proteins
• Groups of genes → Essential genes

Gene

Coordinates: 1,676,033 1,676,389

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• ribosomal protein L19P family (according to Swiss-Prot)

Structure

• 3J9W (the ribosome) PubMed

Expression and Regulation

Operons

• Genes: ylxM-ffh-rpsP-ylqC-ylqD-rimM-trmD-rplS
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulation

  • the mRNA is processed between ffh and rpsP by RNase Y, this requires the YmcA-YlbF-YaaT complex PubMed

• Genes: rplS
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response

  Regulation

  • likely autorepression of rplS expression upon binding of excess RplS to the untranslated region of the rplS mRNA PubMed
  • RelA dependent downregulation (Class I) during stringent response PubMed

References

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